Clinical Study of Integrated Traditional Chinese and Western Medicine in Patients with COPD Chronic Respiratory Failure and Type 2 Diabetes Mellitus with Insulin Resistance
Objective To explore the value of integrated traditional Chinese and Western medicine in the treatment of chronic obstructive pulmonary disease(COPD)with chronic respiratory failure and type 2 diabetes mellitus(T2DM)with insulin resistance.Methods Sixty patients with COPD chronic respiratory failure complicated with T2DM insulin resistance admitted to Dongping County Hospital of Traditional Chinese Medicine from August 2022 to August 2023 were selected as the research objects.They were divided into observation group and control group by different treat-ment methods,with 30 cases in each group.The control group was treated with conventional Western medicine in re-spiratory medicine,and the observation group was treated with traditional Chinese medicine on the basis of the control group.The blood glucose levels[fasting plasma glucose(FPG),2-hour postprandial plasma glucose(2 hPG),glycated hemoglobin A1c(HbA1c)],homeostatic model assessment of insulin resistance(HOMA-IR),blood lipid levels[triglyc-eride(TG),total cholesterol(TC),high density lipoprotein cholesterol(HDL-C)],incidence of adverse reactions(gastro-intestinal reactions,dizziness,palpitations)were compared between the two groups.Results Before treatment,the FPG,2 hPG,HbA1c,HOMA-IR,TG,TC,HDL-C were compared between the two groups,the differences were not statistically significant(all P>0.05).After treatment,HDL-C in the observation group was higher than that in the con-trol group,FPG,2 hPG,HbA1c,HOMA-IR,TG and TC were lower than those in the control group,and the differ-ences were statistically significant(all P<0.05).There was no significant difference in the incidence of adverse reac-tions between the two groups(P>0.05).Conclusion In the clinical treatment of COPD patients with chronic respira-tory failure and T2DM insulin resistance,the combination of traditional Chinese and Western medicine has obvious ef-fect on blood glucose control and blood lipid level improvement,and the safety is high.
Chronic obstructive pulmonary diseaseChronic respiratory failureType 2 diabetes mellitusInsulin re-sistanceIntegrated traditional Chinese and Western medicine
NETL
NSTL
万方数据
