Objective To explore the effect of metformin combined with dapagliflozin on blood glucose level in pa-tients with type 2 diabetes mellitus(T2DM)complicated with acute myocardial infarction.Methods The clinical data of 130 patients with T2DM complicated with acute myocardial infarction admitted to the 73rd Group Military Hospital of Chinese People's Liberation Army from January 2020 to January 2024 were retrospectively selected and divided into two groups according to the different treatment methods,with 65 cases in each group.The conventional group was treated with metformin,and the observation group was treated with metformin combined with dapagliflozin.The blood glucose levels(fasting blood glucose,2-hour postprandial blood glucose,glycated hemoglobin A1c),incidence of ad-verse reactions(low blood pressure,nausea and vomiting,hypoglycemia,headache and dizziness)and clinical efficacy were compared between the two groups.Results After 30 days of treatment,the blood glucose levels of the observation group were lower than that of the conventional group,and the differences were statistically significant(all P<0.05).The clinical efficacy of the observation group was higher than that of the conventional group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Metformin combined with dapagliflozin in the treatment of T2DM complicated with acute myocardial infarction can effectively alleviate the blood glucose level of patients,no significant increase in ad-verse reactions,and the clinical effect is significant.
Type 2 diabetes mellitusAcute myocardial infarctionMetforminDapagliflozinBlood glucose levelsAdverse effects
NETL
NSTL
万方数据
