Objective To explore the clinical efficacy of Qiwei Baizhu Powder in patients with diabetes mellitus.Methods A total of 98 diabetic patients admitted to the Department of Traditional Chinese Medicine of Luocheng Community Health Service Center of Hui'an County from January 2022 to October 2023 as the research objects.Ac-cording to different treatment methods,they were divided into control group and observation group,with 49 cases in each group.Both groups received conventional Western medicine treatment.On this basis,Qiwei Baizhu Powder was added to the observation group.The clinical efficacy,blood glucose index and the incidence of adverse reactions were compared between the two groups.Results The total effective rate of clinical treatment in the observation group was higher than that in the control group,and the blood glucose indexes after treatment were lower than those in the con-trol group,and the differences were statistically significant(all P<0.05).There was no significant difference in the to-tal incidence of adverse reactions between the two groups(P>0.05).Conclusion Diabetic patients combined with Qi-wei Baizhu powder during the application of conventional Western medicine can further improve the effective rate of clinical treatment,significantly reduce blood glucose concentration,and will not increase adverse drug reactions.