首页|血糖控制联合综合康复治疗对T2DM合并脑卒中患者的效果

血糖控制联合综合康复治疗对T2DM合并脑卒中患者的效果

Effect of Blood Glucose Control Combined with Comprehensive Rehabili-tation Therapy on Patients with T2DM Complicated with Stroke

扫码查看
目的 探究2型糖尿病(type 2 diabetes mellitus,T2DM)合并脑卒中患者治疗中选择血糖控制联合综合康复治疗的效果.方法 回顾性选取2022年6月—2024年3月于福建医科大学附属第二医院就诊的76例T2DM合并脑卒中患者的临床资料,按照不同治疗方式分为对照组(二甲双胍缓释片联合综合康复治疗)和研究组(基于对照组治疗方案加入人胰岛素注射液),各38例.比较组间糖代谢水平(餐后2 h血糖、空腹血糖)、临床疗效、不良反应(昏迷、低血糖、恶心/呕吐、皮疹)发生风险.结果 治疗4周后,研究组糖代谢水平低于对照组,差异有统计学意义(P均<0.05).研究组临床疗效高于对照组,差异有统计学意义(P<0.05).两组不良反应发生率比较,差异无统计学意义(P>0.05).结论 在二甲双胍与综合康复治疗基础上加入人胰岛素注射液治疗T2DM合并脑卒中患者,可有效控制糖代谢,疗效显著且不会增加不良反应发生风险,具有较高安全性.
Objective To explore the effect of blood glucose control combined with comprehensive rehabilitation therapy in the treatment of patients with type 2 diabetes mellitus(T2DM)complicated with stroke.Methods The clini-cal data of 76 T2DM patients with stroke who were treated in the Second Affiliated Hospital of Fujian Medical Univer-sity from June 2022 to March 2024 were retrospectively selected.According to different treatment methods,they were divided into the control group(metformin sustained release tablets combined with comprehensive rehabilitation treat-ment)and the study group(human insulin injection was added based on the treatment plan of the control group),with 38 cases in each group.The levels of glucose metabolism(2-hour postprandial blood glucose,fasting blood glucose),clinical efficacy,and the risk of adverse reactions(coma,hypoglycemia,nausea/vomiting,rash)were compared be-tween the two groups.Results After 4 weeks of treatment,the glucose metabolism level of the study group were lower than those of the control group,and the differences were statistically significant(both P<0.05).The clinical efficacy of the study group was higher than that of the control group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion On the basis of metformin and comprehensive rehabilitation therapy,human insulin injection is added to treat patients with T2DM complicated with stroke,which can effectively control glucose metabolism,has significant cu-rative effect and does not increase the risk of adverse reactions,and has high safety.

Type 2 diabetes mellitusStrokeComprehensive rehabilitation therapyBlood glucose controlClinical efficacyAdverse effects

陈跃进、许丹香、黄庭龙

展开 >

福建医科大学附属第二医院,福建 泉州 362200

2型糖尿病 脑卒中 综合康复治疗 血糖控制 临床疗效 不良反应

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(11)