首页|百令胶囊联合二甲双胍治疗糖尿病肾病的临床价值研究

百令胶囊联合二甲双胍治疗糖尿病肾病的临床价值研究

Clinical Value of Bailing Capsule Combined with Metformin in the Treat-ment of Diabetes Nephropathy

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目的 分析二甲双胍联合百令胶囊治疗糖尿病肾病的效果.方法 选取2022年8月—2023年8月枣庄市皮肤病性病防治院收治的66例糖尿病肾病患者为研究对象,按照不同治疗方法分为两组,各33例.对照组行二甲双胍治疗,观察组行二甲双胍联合百令胶囊治疗.对比两组治疗有效率、血糖指标(空腹血糖、餐后2 h血糖、糖化血红蛋白、胰岛素抵抗指数)、肾功能指标(24 h尿蛋白排泄率、血肌酐、血尿素氮).结果 观察组治疗总有效率为93.94%(31/33),高于对照组的72.73%(24/33),差异有统计学意义(χ2=5.345,P=0.020).观察组治疗各项血糖相关指标、肾功能指标均低于对照组,差异有统计学意义(P均<0.05).结论 二甲双胍联合百令胶囊治疗糖尿病肾病的效果优于单纯使用二甲双胍,临床应用价值较高.
Objective To analyze the therapeutic effect of metformin combined with Bailing Capsule in the treatment of diabetic nephropathy.Methods A total of 66 patients with diabetic nephropathy admitted to Zaozhuang Dermatol-ogy and Venereal Disease Prevention and Control Hospital from August 2022 to August 2023 were selected as the re-search objects.According to different treatment methods,they were divided into two groups,33 cases in each group.The control group was treated with metformin,and the observation group was treated with metformin combined with Bailing Capsule.The effective rate of treatment,blood glucose indexes(fasting blood glucose,2-hour postprandial blood glucose,glycated hemoglobin A1c,insulin resistance index),renal function indexes(24 h urinary protein excre-tion rate,serum creatinine,blood urea nitrogen)were compared between the two groups.Results The total effective rate of treatment of the observation group was 93.94%(31/33),which was higher than 72.73%(24/33)of the control group,and the difference was statistically significant(χ2=5.345,P=0.020).The blood glucose related indexes and re-nal function indexes in the observation group were lower than those in the control group,and the differences were sta-tistically significant(all P<0.05).Conclusion The effect of metformin combined with Bailing Capsule in the treatment of diabetic nephropathy is better than that of metformin alone,and the clinical application value is high.

Diabetes nephropathyMetforminBailing CapsulesRenal functionBlood glucose

赵林、高媛

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枣庄市皮肤病性病防治院内一科,山东 滕州 277599

糖尿病肾病 二甲双胍 百令胶囊 肾功能 血糖

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(12)