Objective To explore the application effect of glycosylated hemoglobin A1c(HbA1c)combined with glu-cose tolerance test in the diagnosis of gestational diabetes mellitus(GDM).Methods A total of 163 GDM patients(ob-servation group)and 163 healthy pregnant women(control group)who visited the Maternal and Child Health Hospital of Boshan Family Planning Service Center of Zibo City from January 2022 to March 2024 were selected as the study objects.HbA1c and glucose tolerance tests were performed in both groups,and fasting plasma glucose,HbA1c,blood glucose at 1 h and 2 h after taking glucose were compared between the two groups.Receiver operating characteristic(ROC)curve was used to analyze the diagnostic efficiency of single index detection and combined detection.Results ROC curve analysis results showed that the combined detection of HbA1c and glucose tolerance had the highest diag-nostic efficiency in GDM diagnosis(area under the curve:0.999,95%CI:0.986-1.000,sensitivity was 98.77%,speci-ficity was 98.16%).Conclusion The diagnostic value of HbA1c combined with glucose tolerance test results in GDM diagnosis is high.
维普
万方数据
