糖尿病新世界2024,Vol.27Issue(12) :50-52.DOI:10.16658/j.cnki.1672-4062.2024.12.050

β2-微球蛋白与血肌酐/血红蛋白比值联合检验结果在糖尿病早期肾损伤诊断中的应用价值

Application Value of Combined Test Results of β2-microglobulin and Se-rum Creatinine/Hemoglobin Ratio in the Diagnosis of Early Renal Injury in Diabetes Mellitus

张鹏 程贝 朱宇 王翔
糖尿病新世界2024,Vol.27Issue(12) :50-52.DOI:10.16658/j.cnki.1672-4062.2024.12.050

β2-微球蛋白与血肌酐/血红蛋白比值联合检验结果在糖尿病早期肾损伤诊断中的应用价值

Application Value of Combined Test Results of β2-microglobulin and Se-rum Creatinine/Hemoglobin Ratio in the Diagnosis of Early Renal Injury in Diabetes Mellitus

张鹏 1程贝 1朱宇 1王翔1
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作者信息

  • 1. 泰兴市中医院检验科,江苏 泰兴 225400
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摘要

目的 分析β2-微球蛋白(β2-microglobulin,β2-MG)与血肌酐/血红蛋白比值联合检验诊断糖尿病早期肾损伤的价值.方法 选取2022年7月—2024年1月泰兴市中医院收治的82例糖尿病患者为研究对象,其中60例为单纯糖尿病患者,22例为糖尿病早期肾损伤患者,所有患者进行β2-MG、血肌酐/血红蛋白比值检测,对比不同检查方法的诊断价值(准确度、灵敏度、特异度).结果 β2-MG联合血肌酐/血红蛋白比值检测的灵敏度、准确度高于β2-MG、血肌酐/血红蛋白比值单独检测,差异有统计学意义(P均<0.05).β2-MG与血肌酐/血红蛋白比值检测的灵敏度、特异度、准确度对比,差异无统计学意义(P均>0.05).结论 β2-MG与血肌酐/血红蛋白比值联合检验诊断糖尿病早期肾损伤的灵敏度、准确度均高于单一β2-MG、血肌酐/血红蛋白比值检测.

Abstract

Objective To analyze the value of combined test of β2-microglobulin(β2-MG)and serum creatinine/he-moglobin ratio in the diagnosis of early renal injury in diabetes mellitus.Methods A total of 82 diabetic patients ad-mitted to Taixing Hospital of Traditional Chinese Medicine from July 2022 to January 2024 were selected as the re-search objects,including 60 patients with simple diabetes mellitus and 22 patients with early renal injury in diabetes mellitus.All patients were tested for β2-MG and serum creatinine/hemoglobin ratio,and the diagnostic values(accu-racy,sensitivity and specificity)of different examination methods were compared.Results The sensitivity and accu-racy of β2-MG combined with serum creatinine/hemoglobin ratio were higher than those of β2-MG and serum cre-atinine/hemoglobin ratio,and the differences were statistically significant(all P<0.05).There were no significant dif-ference in sensitivity,specificity and accuracy between β2-MG and serum creatinine/hemoglobin ratio(all P>0.05).Conclusion The sensitivity and accuracy of combined detection of β2-MG and serum creatinine/hemoglobin ratio in the diagnosis of early renal injury in diabetes mellitus were higher than those of single β2-MG and serum creatinine/hemoglobin ratio.

关键词

β2-微球蛋白/血肌酐/血红蛋白比值/联合检验/糖尿病/早期肾损伤

Key words

β2-microglobulin/Serum creatinine/hemoglobin ratio/Combined test/Diabetes mellitus/Early renal in-jury

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出版年

2024
糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
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