首页|β2-微球蛋白与血肌酐/血红蛋白比值联合检验结果在糖尿病早期肾损伤诊断中的应用价值

β2-微球蛋白与血肌酐/血红蛋白比值联合检验结果在糖尿病早期肾损伤诊断中的应用价值

Application Value of Combined Test Results of β2-microglobulin and Se-rum Creatinine/Hemoglobin Ratio in the Diagnosis of Early Renal Injury in Diabetes Mellitus

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目的 分析β2-微球蛋白(β2-microglobulin,β2-MG)与血肌酐/血红蛋白比值联合检验诊断糖尿病早期肾损伤的价值.方法 选取2022年7月—2024年1月泰兴市中医院收治的82例糖尿病患者为研究对象,其中60例为单纯糖尿病患者,22例为糖尿病早期肾损伤患者,所有患者进行β2-MG、血肌酐/血红蛋白比值检测,对比不同检查方法的诊断价值(准确度、灵敏度、特异度).结果 β2-MG联合血肌酐/血红蛋白比值检测的灵敏度、准确度高于β2-MG、血肌酐/血红蛋白比值单独检测,差异有统计学意义(P均<0.05).β2-MG与血肌酐/血红蛋白比值检测的灵敏度、特异度、准确度对比,差异无统计学意义(P均>0.05).结论 β2-MG与血肌酐/血红蛋白比值联合检验诊断糖尿病早期肾损伤的灵敏度、准确度均高于单一β2-MG、血肌酐/血红蛋白比值检测.
Objective To analyze the value of combined test of β2-microglobulin(β2-MG)and serum creatinine/he-moglobin ratio in the diagnosis of early renal injury in diabetes mellitus.Methods A total of 82 diabetic patients ad-mitted to Taixing Hospital of Traditional Chinese Medicine from July 2022 to January 2024 were selected as the re-search objects,including 60 patients with simple diabetes mellitus and 22 patients with early renal injury in diabetes mellitus.All patients were tested for β2-MG and serum creatinine/hemoglobin ratio,and the diagnostic values(accu-racy,sensitivity and specificity)of different examination methods were compared.Results The sensitivity and accu-racy of β2-MG combined with serum creatinine/hemoglobin ratio were higher than those of β2-MG and serum cre-atinine/hemoglobin ratio,and the differences were statistically significant(all P<0.05).There were no significant dif-ference in sensitivity,specificity and accuracy between β2-MG and serum creatinine/hemoglobin ratio(all P>0.05).Conclusion The sensitivity and accuracy of combined detection of β2-MG and serum creatinine/hemoglobin ratio in the diagnosis of early renal injury in diabetes mellitus were higher than those of single β2-MG and serum creatinine/hemoglobin ratio.

β2-microglobulinSerum creatinine/hemoglobin ratioCombined testDiabetes mellitusEarly renal in-jury

张鹏、程贝、朱宇、王翔

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泰兴市中医院检验科,江苏 泰兴 225400

β2-微球蛋白 血肌酐/血红蛋白比值 联合检验 糖尿病 早期肾损伤

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(12)