Objective To analyze the efficacy and safety of different insulin administration methods in the treatment of diabetic ketoacidosis in ICU.Methods The clinical data of 98 patients with diabetic ketoacidosis admitted to Quan-zhou First Hospital from January 2023 to February 2024 were retrospectively selected and divided into two groups ac-cording to different treatment methods,with 49 cases in each group.The insulin use in the control group was intrave-nous drip,and the insulin use in the study group was subcutaneous pumping.The clinical efficacy,adverse reactions(infection,hyperchloremia,hypoglycemia),symptom improvement time(blood glucose standard time,urine ketone body negative time,blood ketone body recovery time)and blood glucose index(fasting blood glucose,2-hour postpran-dial blood glucose,glycated hemoglobin A1c)levels were compared between the two groups.Results The total treat-ment effective rate of the study group was higher than that of the control group,and the difference was statistically sig-nificant(P<0.05).The improvement time of symptoms in the study group were shorter than those in the control group,and the differences were statistically significant(all P<0.05).After treatment,the blood glucose levels of the study group were lower than those of the control group,and the differences were statistically significant(all P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Subcutaneous insulin pumping is a safe,effective and reliable method for the treatment of ICU patients with diabetic ketoacidosis,which can improve clinical efficacy,reduce blood glucose level,and promote the remission of disease symptoms with high safety.
维普
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