Objective To analyze the related risk factors of gestational diabetes mellitus(GDM),and to provide the ba-sis for the comprehensive prevention and control of GDM.Methods The clinical data of 100 patients with GDM(GDM group)and 100 pregnant women with non-gestational diabetes mellitus(control group)who received medical treatment in People's Hospital of Rizhao from January 2021 to June 2023 were retrospectively selected,and the relevant clinical data of the two groups were analyzed by univariate analysis and multivariate Logistic regression analysis.The risk fac-tors of GDM were analyzed.Results Age ≥35 years old,body mass index ≥25 kg/m2 and family history of diabetes were independent risk factors for GDM(all P<0.05).Conclusion Age ≥35 years old,body mass index ≥25 kg/m2,and family history of diabetes are independent risk factors for GDM.GDM nursing management should be strengthened to ensure the safety of mother and child.