Objective To study the application of dexmedetomidine in patients with type 2 diabetes mellitus under general anesthesia and its effect on hemodynamics and blood glucose changes.Methods A total of 120 patients with type 2 diabetes who underwent general anesthesia in Zhongshan Hospital Xiamen University from December 2022 to February 2024 were selected as the study subjects.They were divided into two groups according to different anesthe-sia methods,60 cases in each group.The control group was given normal saline to maintain anesthesia during opera-tion,and the observation group was treated with dexmedetomidine.The hemodynamics,blood glucose changes,anes-thesia recovery indexes and anesthesia safety were compared between the two groups.Results The heart rate and mean arterial pressure at intubation,skin incision and extubation in the observation group were lower than those in the control group,and the differences were statistically significant(all P<0.05).The fasting plasma glucose levels at the end of operation and 6 h after operation in the observation group were lower than those in the control group,and the differences were statistically significant(both P<0.05).The eye opening time,extubation time and spontaneous breath-ing recovery time in the observation group were longer than those in the control group,and the differences were statis-tically significant(all P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The application of dexmedetomidine in the treatment of patients with type 2 diabe-tes under general anesthesia has a certain impact on the quality of anesthesia recovery,but it can better stabilize he-modynamics and blood glucose values,and ensure the safety of medication.
Type 2 diabetes mellitusDexmedetomidineGeneral anesthesiaHemodynamicsBlood glucose changes
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