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即时检验糖化血红蛋白用于诊断妊娠期糖尿病的价值

Value of Immediate Detection of Glycated Hemoglobin A1c in the Diagno-sis of Gestational Diabetes Mellitus

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目的 探究即时检验糖化血红蛋白(glycated hemoglobin A1c,HbA1c)在妊娠期糖尿病临床诊断中的价值.方法 选取2021年7月—2023年7月泉州医学高等专科学校附属人民医院收治的240例疑似妊娠期糖尿病患者为研究对象,实施即时HbA1c检测及空腹血糖(fasting plasma glucose,FPG)检测,以葡萄糖耐量试验为金标准,分析不同检查方法的灵敏度、特异度、准确度、阳性预测值、阴性预测值.结果 HbAlc检测特异度、准确度、阳性预测值均高于FPG检测,差异有统计学意义(P均<0.05),、两种检测方式的阴性预测值、灵敏度比较,差异无统计学意义(P均>0.05).结论 即时HbA1c检测可提高妊娠期糖尿病检测结果的准确度,有利于及时发现妊娠期女性的异常血糖情况.
Objective To explore the value of immediate detection of glycated hemoglobin A1c(HbA1c)in the clini-cal diagnosis of gestational diabetes mellitus.Methods A total of 240 patients with suspected gestational diabetes mel-litus admitted to People's Hospital Affiliated of Quanzhou Medical College from July 2021 to July 2023 were selected as the study subjects.Immediate detection of HbA1c and fasting plasma glucose(FPG)were tested.Using the oral glu-cose tolerance test as the gold standard,the sensitivity,specificity,accuracy,positive predictive value and negative predictive value of the different methods were analyzed.Results The specificity,accuracy and positive predictive value of HbAlc detection were higher than those of FPG detection,and the differences were statistically significant(all P<0.05).The negative predictive value and sensitivity of the two detection methods were not statistically signifi-cant(both P>0.05).Conclusion Immediate of HbA1c detection can improve the accuracy of gestational diabetes melli-tus detection results,which is conducive to timely detection of abnormal blood glucose in pregnant women.

Immediate detectionGlycated hemoglobin A1cGestational diabetes mellitus

熊再霞、黄菲凤、李丽红

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泉州医学高等专科学校附属人民医院妇产科,福建 泉州 362000

即时检验 糖化血红蛋白 妊娠期糖尿病

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(14)