Objective To analyze the effects of intravenous insulin infusion and continuous subcutaneous insulin pump for patients with severe diabetic ketoacidosis(DKA).Methods A total of 60 patients with severe DKA admitted to the Department of Intensive Care Medicine of Hui'an County General Hospital of Quanzhou City,Fujian Province from June 2021 to March 2024 were selected as the study objects,and were divided into control group and observation group according to different treatment methods,with 30 cases in each group.The control group was treated with intra-venous insulin infusion,and the observation group was given continuous insulin infusion via insulin pump.The clini-cal indexes,blood glucose indexes,clinical efficacy and adverse reactions were compared between the two groups.Results The insulin dose and pH recovery time in the observation group were less than those in the control group,and the glutathione peroxidase,superoxide dismutase and total antioxidant capacity were higher than those in the control group,the differences were statistically significant(all P<0.05).After treatment,the fasting blood glucose and 2-hour postprandial blood glucose in the observation group were lower than those in the control group,and the differences were statistically significant(both P<0.05).The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the obser-vation group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion Continuous subcutaneous insulin pump injection in the treatment of severe DKA patients can effectively improve its clinical efficacy and provide a guarantee for patient safety.
Insulin pumpContinuous subcutaneous injectionIntravenous infusionSevere diabetic ketoacidosisBlood glucose index
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