糖尿病新世界2024,Vol.27Issue(14) :105-108.DOI:10.16658/j.cnki.1672-4062.2024.14.105

四联方案联合维生素C对2型糖尿病合并胃溃疡患者血糖水平的影响

Effect of Quadruple Regimen Combined with Vitamin C on Blood Glucose Level in Patients with Type 2 Diabetes Mellitus Complicated with Gastric Ulcer

黄小聪 许丽宣 赖冬梅
糖尿病新世界2024,Vol.27Issue(14) :105-108.DOI:10.16658/j.cnki.1672-4062.2024.14.105

四联方案联合维生素C对2型糖尿病合并胃溃疡患者血糖水平的影响

Effect of Quadruple Regimen Combined with Vitamin C on Blood Glucose Level in Patients with Type 2 Diabetes Mellitus Complicated with Gastric Ulcer

黄小聪 1许丽宣 1赖冬梅1
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作者信息

  • 1. 泉州市光前医院,福建 泉州 362321
  • 折叠

摘要

目的 探究四联方案联合维生素C对2型糖尿病合并胃溃疡患者血糖水平的影响.方法 回顾性选取2023年6月—2024年3月泉州市光前医院收治的108例糖尿病合并胃溃疡患者的临床资料,根据治疗方式不同分为两组,各54例.两组均使用胰岛素治疗,对照组使用四联方案治疗,研究组采用四联方案联合维生素C治疗.比较两组血糖水平、不良反应、胃功能.结果 治疗后,研究组空腹血糖、餐后2 h血糖均低于对照组,差异有统计学意义(P均<0.05).两组不良反应发生率对比,差异无统计学意义(P>0.05).治疗后,研究组胃泌素-17、胃蛋白酶原-1、胃蛋白酶原-2均低于对照组,差异有统计学意义(P均<0.05).结论 四联方案联合维生素C治疗2型糖尿病合并胃溃疡患者,能够降低血糖水平,且不良反应风险较低,有助于患者胃功能提升.

Abstract

Objective To explore the effect of quadruple regimen combined with vitamin C on blood glucose level in patients with type 2 diabetes mellitus complicated with gastric ulcer.Methods Clinical data of 108 patients with dia-betes mellitus complicated with gastric ulcer admitted to Quanzhou Guangqian Hospital from June 2023 to March 2024 were retrospectively selected and divided into two groups according to different treatment methods,with 54 cases in each group.Both groups were treated with insulin,the control group was treated with quadruple regimen,and the study group was treated with quadruple regimen combined with vitamin C.Blood glucose levels,adverse reactions,and gastric function were compared between the two groups.Results After treatment,fasting blood glucose and 2-hour postprandial blood glucose in the study group were lower than those in the control group,and the differences were sta-tistically significant(both P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).After treatment,gastrin-17,pepsinogen 1 and pepsinogen 2 in the study group were lower than those in the control group,and the differences were statistically significant(all P<0.05).Conclusion Quadruple regimen combined with vitamin C in the treatment of patients with type 2 diabetes mellitus complicated with gastric ul-cer can reduce the blood glucose level,and the risk of adverse reactions is low,which is helpful to improve the gastric function of patients.

关键词

四联方案/维生素C/糖尿病/胃溃疡/血糖水平

Key words

Quadruple plan/Vitamin C/Diabetes mellitus/Gastric ulcer/Blood glucose level

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出版年

2024
糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
参考文献量12
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