糖尿病新世界2024,Vol.27Issue(14) :172-175.DOI:10.16658/j.cnki.1672-4062.2024.14.172

不同胰岛素给药方式对急诊糖尿病酮症酸中毒患者的预后效果影响

Impact of Different Insulin Administration Modalities on the Prognostic Outcome of Patients with Diabetic Ketoacidosis in the Emergency Setting

吴君君 谢卫妹 林瑜萍
糖尿病新世界2024,Vol.27Issue(14) :172-175.DOI:10.16658/j.cnki.1672-4062.2024.14.172

不同胰岛素给药方式对急诊糖尿病酮症酸中毒患者的预后效果影响

Impact of Different Insulin Administration Modalities on the Prognostic Outcome of Patients with Diabetic Ketoacidosis in the Emergency Setting

吴君君 1谢卫妹 1林瑜萍1
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作者信息

  • 1. 福建医科大学附属第二医院(东海院区)急诊科,福建 泉州 362000
  • 折叠

摘要

目的 探究急诊糖尿病酮症酸中毒(diabetic ketoacidosis,DKA)患者治疗中不同胰岛素给药方式的应用价值.方法 回顾性选取2023年4月—2024年3月福建医科大学附属第二医院收治的124例急诊DKA患者的临床资料,通过不同胰岛素给药方式分为常规组(胰岛素皮下注射给药)和观察组(胰岛素微量泵注给药),各62例.对比两组临床疗效、糖代谢水平及临床指标.结果 观察组治疗总有效率高于常规组,差异有统计学意义(P<0.05).治疗后,观察组糖化血红蛋白、餐后2 h血糖、空腹血糖水平均低于常规组,差异有统计学意义(P均<0.05).观察组尿酮体恢复时间、pH值恢复时间、血酮体恢复时间均短于常规组,差异有统计学意义(P均<0.05).结论 急诊DKA患者治疗中选择胰岛素微量泵注给药方式,可提高临床疗效,有效控制血糖水平并改善临床指标.

Abstract

Objective To explore the application value of different insulin administration methods in the treatment of emergency diabetic ketoacidosis(DKA)patients.Methods The clinical data of 124 patients with emergency DKA ad-mitted to the Second Affiliated Hospital of Fujian Medical University from April 2023 to March 2024 were retrospec-tively selected.They were divided into routine group(subcutaneous injection of insulin)and observation group(micro-pump injection of insulin)by different insulin administration methods,with 62 cases in each group.The clinical effi-cacy,glucose metabolism levels and clinical indicators were compared between the two groups.Results The total ef-fective rate of the observation group was higher than that of the routine group,and the difference was statistically sig-nificant(P<0.05).After treatment,the levels of glycated hemoglobin A1c,2-hour postprandial blood glucose and fast-ing blood glucose in the observation group were lower than those in the routine group,and the differences were statisti-cally significant(all P<0.05).The recovery time of urine ketone body,pH value and blood ketone body in the observa-tion group were shorter than those in the routine group,and the differences were statistically significant(all P<0.05).Conclusion The selection of insulin micropump injection in the treatment of emergency DKA patients can improve the clinical efficacy,effectively control the blood glucose levels and improve the clinical indicators.

关键词

糖尿病酮症酸中毒/胰岛素/微量泵注/皮下注射/糖代谢

Key words

Diabetic ketoacidosis/Insulin/Micropumping/Subcutaneous injection/Glucose metabolism

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出版年

2024
糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
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