糖尿病新世界2024,Vol.27Issue(14) :184-187.DOI:10.16658/j.cnki.1672-4062.2024.14.184

胰岛素微量注射泵输注对糖尿病酮症酸中毒患者血糖水平的影响

Effect of Insulin Microinjection Pump Infusion on Blood Glucose Levels in Patients with Diabetic Ketoacidosis

王巧霞 俞艳青 陈锦云
糖尿病新世界2024,Vol.27Issue(14) :184-187.DOI:10.16658/j.cnki.1672-4062.2024.14.184

胰岛素微量注射泵输注对糖尿病酮症酸中毒患者血糖水平的影响

Effect of Insulin Microinjection Pump Infusion on Blood Glucose Levels in Patients with Diabetic Ketoacidosis

王巧霞 1俞艳青 1陈锦云1
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作者信息

  • 1. 陆军第七十三集团军医院,福建 厦门 361000
  • 折叠

摘要

目的 分析胰岛素微量注射泵输注对糖尿病酮症酸中毒患者血糖水平的影响.方法 回顾性选取2023年5月—2024年3月陆军第七十三集团军医院收治的96例糖尿病酮症酸中毒患者的临床资料,根据治疗方式不同分为两组,各48例.对照组治疗方式为胰岛素静脉滴注,研究组治疗方式为胰岛素微量注射泵输注.比较两组血糖水平、胰岛功能、临床指标及不良反应发生情况.结果 研究组血糖达标时间、尿酮体转阴时间、血酮体恢复时间、住院时间均短于对照组,差异有统计学意义(P均<0.05).治疗后,研究组糖化血红蛋白、空腹血糖、餐后2 h血糖水平均低于对照组,差异有统计学意义(P均<0.05).治疗后,研究组空腹胰岛素、胰岛β细胞功能指数、胰岛素抵抗指数优于对照组,差异有统计学意义(P均<0.05).研究组不良反应发生率低于对照组,差异有统计学意义(P<0.05).结论 胰岛素微量注射泵输注对糖尿病酮症酸中毒患者治疗效果较好、不良反应发生风险较低,还能够降低血糖水平、改善胰岛功能,促进患者康复.

Abstract

Objective To analyze the effect of insulin microinjection pump infusion on blood glucose levels in patients with diabetic ketoacidosis.Methods The clinical data of 96 patients with diabetic ketoacidosis admitted to Army 73rd Group Military Hospital from May 2023 to March 2024 were retrospectively selected and divided into two groups ac-cording to different treatment methods,with 48 cases in each group.The control group was treated with insulin intrave-nous drip,and the study group was treated with insulin microinjection pump infusion.The blood glucose levels,islet function,clinical indicators and adverse reactions were compared between the two groups.Results The time of blood glucose reaching the standard,the time of urine ketone body turning negative,the time of blood ketone body recovery and the time of hospitalization in the study group were shorter than those in the control group,and the differences were statistically significant(all P<0.05).After treatment,the levels of glycated hemoglobin A1c,fasting blood glucose and 2-hour postprandial blood glucose in the study group were lower than those in the control group,and the differ-ences were statistically significant(all P<0.05).After treatment,the fasting insulin,islet β cell function index and in-sulin resistance index in the study group were better than those in the control group,and the differences were statisti-cally significant(all P<0.05).The incidence of adverse reactions in the study group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion Insulin microinjection pump infusion has a good therapeutic effect on patients with diabetic ketoacidosis,and the risk of adverse reactions is low.It can also re-duce blood glucose levels,improve islet function,and promote patient recovery.

关键词

胰岛素/微量注射泵/糖尿病/血糖水平/临床指标

Key words

Insulin/Microinjection pump/Diabetes mellitus/Blood glucose level/Clinical index

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出版年

2024
糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
参考文献量10
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