首页|眼底激光与康柏西普联合治疗糖尿病性视网膜病变的疗效及安全性探讨

眼底激光与康柏西普联合治疗糖尿病性视网膜病变的疗效及安全性探讨

Investigate the Efficacy and Safety of Fundus Laser Combined with Con-bercept in the Treatment of Diabetic Retinopathy

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目的 探究糖尿病性视网膜病变患者应用眼底激光联合康柏西普的作用效果.方法 选取句容市人民医院2023年1月—2024年2月收治的66例患者为研究对象,根据治疗方法不同分为观察组(33例,54只眼)、对照组(33例,54只眼).对照组应用康柏西普治疗,观察组在对照组的基础上应用眼底激光治疗.比较两组临床疗效、视网膜相关指标、不良反应发生率.结果 观察组治疗有效率高于对照组,差异有统计学意义(P<0.05).观察组黄斑中心凹视网膜厚度低于对照组,最佳矫正视力水平高于对照组,差异有统计学意义(P均<0.05).两组不良反应发生率比较,差异无统计学意义(P>0.05).结论 眼底激光与康柏西普联合治疗能够提高糖尿病性视网膜病变患者的治疗效果,改善其视网膜相关指标,且安全性较好,具有重要的临床借鉴价值.
Objective To explore the effect of fundus laser combined with conbercept in patients with diabetic reti-nopathy.Methods A total of 66 patients admitted to Jurong People's Hospital from January 2023 to February 2024 were selected as the research objects.According to different treatment methods,they were divided into observation group(33 cases,54 eyes)and control group(33 cases,54 eyes).The control group was treated with conbercept,and the observation group was treated with fundus laser on the basis of the control group.The clinical efficacy,retinal re-lated indexes and incidence of adverse reactions were compared between the two groups.Results The effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically signifi-cant(P<0.05).The macular foveal retinal thickness of the observation group was lower than that of the control group,and the best corrected visual acuity level was higher than that of the control group,the differences were statistically significant(both P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The combination of fundus laser and conbercept can improve the therapeutic effect of patients with diabetic retinopathy,improve their retinal related indicators,and have good safety,which has important clinical reference value.

Fundus laserConberceptDiabetic retinopathyTherapeutic effect

李军炬、钟雪梅、徐鸿飞

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句容市人民医院眼科,江苏 镇江 221400

眼底激光 康柏西普 糖尿病性视网膜病变 治疗效果

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(15)