Objective To investigate the effect of recombinant human erythropoietin and iron sucrose in the treatment of diabetic nephropathy patients with hemodialysis.Methods A total of 90 diabetic nephropathy patients admitted to Xiamen Third Hospital from March 2022 to March 2024 were selected as the study objects.According to different treatment methods,they were divided into control group(given recombinant human erythropoitin,45 cases)and obser-vation group(given recombinant human erythropoitin and iron sucrose,45 cases).Blood glucose indexes,anemia in-dexes,iron metabolism indexes,renal function indexes and total effective rate of treatment were compared between the two groups.Results After treatment,the levels of fasting blood glucose,2-hour postprandial blood glucose,glycated hemoglobin A1c and glycated albumin in observation group were lower than those in control group,and the differences were statistically significant(all P<0.05).After treatment,the hemoglobin level,mean erythrocyte hemoglobin concen-tration,erythrocyte count and hematocrit in observation group were higher than those in control group,and the differ-ences were statistically significant(all P<0.05).After treatment,the serum creatinine,serum urea nitrogen,blood uric acid and urinary albumin excretion rate in observation group were lower than those in control group,and the differ-ences were statistically significant(all P<0.05).After treatment,ferrimodulin in observation group was lower than that in control group,and ferritin,transferrin and transferrin saturation were higher than those in control group,and the dif-ferences were statistically significant(all P<0.05).The total effective rate of treatment in the observation group was higher than that of the control group,the difference was statistically significant(P<0.05).Conclusion The treatment of diabetic nephropathy hemodialysis patients with sucrose iron combined with recombinant human erythropoietin can not only maintain stable blood glucose,promote the recovery of renal function,but also improve anemia and improve the therapeutic effect.
Diabetic nephropathyHemodialysisIron sucroseRecombinant human erythropoietinAnemic state
维普
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