糖尿病新世界2024,Vol.27Issue(20) :26-28,34.DOI:10.16658/j.cnki.1672-4062.2024.20.026

高原地区糖尿病患儿维生素D水平的影响因素分析

Analysis of Influencing Factors of Vitamin D Level in Children with Diabe-tes in Plateau Area

刘志兰 孙雨葳 谢雨桐
糖尿病新世界2024,Vol.27Issue(20) :26-28,34.DOI:10.16658/j.cnki.1672-4062.2024.20.026

高原地区糖尿病患儿维生素D水平的影响因素分析

Analysis of Influencing Factors of Vitamin D Level in Children with Diabe-tes in Plateau Area

刘志兰 1孙雨葳 1谢雨桐2
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作者信息

  • 1. 青海省妇女儿童医院内分泌科,青海 西宁 810007
  • 2. 青海省妇女儿童医院检验科,青海 西宁 810007
  • 折叠

摘要

目的 探讨高原地区糖尿病患儿维生素D水平的影响因素.方法 回顾性选取2017年6月—2022年6月青海省妇女儿童医院内分泌科收治的122例居住地海拔≥2 100 m的糖尿病患儿的临床资料.根据不同的维生素D水平,分为维生素D不正常组(<20 ng/mL)60例和维生素D正常组(≥20 ng/mL)62例.收集两组一般资料、生理生化指标,进行单因素及多因素Logistic回归分析.结果 两组性别、低密度脂蛋白、总胆固醇比较,差异均有统计学意义(P均<0.05).多因素Logistic回归分析结果显示,低密度脂蛋白>3.4 mmol/L是高原地区糖尿病患儿发生低水平维生素D的危险因素(P<0.05).结论 在高原地区儿童糖尿病患者中,维生素D水平与性别、低密度脂蛋白和总胆固醇存在一定联系,其中低密度脂蛋白是维生素D水平的影响因素.

Abstract

Objective To explore the influencing factors of vitamin D level in children with diabetes in plateau area.Methods The clinical data of 122 children with diabetes living at an altitude of≥2 100 m admitted to the Department of Endocrinology in Qinghai Women and Children's Hospital from June 2017 to June 2022 were retrospectively se-lected.According to different vitamin D levels,they were divided into vitamin D abnormal group(<20 ng/mL)of 60 cases and vitamin D normal group(≥20 ng/mL)of 62 cases.The general data,physiological and biochemical indexes of the two groups were collected for univariate and multiple Logistic regression analysis.Results There were signifi-cant differences in gender,low density lipoprotein and total cholesterol between the two groups(all P<0.05).Multiple Logistic regression analysis showed that low density lipoprotein>3.4 mmol/L was a risk factor for low level of vitamin D in children with diabetes in plateau area(P<0.05).Conclusion In children with diabetes in plateau area,vitamin D level is related to gender,low density lipoprotein and total cholesterol,and low density lipoprotein is the influencing factor of vitamin D level.

关键词

维生素D/高原地区/糖尿病患儿/影响因素

Key words

Vitamin D/Plateau areas/Children with diabetes/Influencing factor

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出版年

2024
糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
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