首页|血清C肽联合糖化血红蛋白检验在糖尿病临床诊断中的应用效果及准确度分析

血清C肽联合糖化血红蛋白检验在糖尿病临床诊断中的应用效果及准确度分析

Application Effect and Accuracy Analysis of Serum C-peptide Combined with Glycated Hemoglobin A1c Test in the Clinical Diagnosis of Diabetes Mellitus

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目的 分析血清C肽联合糖化血红蛋白检验诊断糖尿病的准确度.方法 选取2022年3月—2024年3月北京昌平区医院收治的60例疑似糖尿病患者作为研究对象,所有患者均开展血清C肽及糖化血红蛋白检验,以口服葡萄糖耐量试验作为糖尿病的诊断金标准,比较血清C肽联合糖化血红蛋白检验与单一检测的诊断效能.结果 口服葡萄糖耐量试验诊断阳性48例,阴性12例;血清C肽检验检出阳性39例,阴性21例;糖化血红蛋白检验检出阳性40例,阴性20例;血清C肽联合糖化血红蛋白检验检出阳性47例,阴性13例.联合检验的准确度、特异度、灵敏度均高于血清C肽、糖化血红蛋白单一检验,差异均有统计学意义(P均<0.05).结论 血清C肽联合糖化血红蛋白水平检测糖尿病的诊断效能高于单一检测,有较高的应用价值.
Objective To analyze the accuracy of serum C-peptide combined with glycated hemoglobin A1c test in the diagnosis of diabetes mellitus.Methods A total of 60 patients with suspected diabetes mellitus admitted to Beijing Changping Hospital from March 2022 to March 2024 were selected as the research objects.All patients underwent se-rum C-peptide and glycated hemoglobin A1c test.Oral glucose tolerance test was used as the gold standard for the di-agnosis of diabetes mellitus.The diagnostic efficacy of serum C-peptide combined with glycated hemoglobin A1c test and single detection was compared.Results Oral glucose tolerance test confirmed positive 48 cases,negative in 12 cases.Serum C-peptide test detected positive in 39 cases and negative in 21 cases,glycated hemoglobin A1c test de-tected positive in 40 cases and negative in 20 cases,serum C-peptide combined with glycated hemoglobin A1c test detected 47 positive cases and 13 negative cases.The accuracy,specificity and sensitivity of the combined test were higher than those of the single test of serum C peptide and glycated hemoglobin A1c,and the differences were statisti-cally significant(all P<0.05).Conclusion The diagnostic efficacy of serum C-peptide combined with glycated hemo-globin A1c is higher than that of single detection,and it has high application value.

Diabetes mellitusDiagnosisSerum C-peptideGlycated hemoglobin A1cAccuracy

宿欣、赵文吉、高玲

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北京昌平区医院检验科,北京 102200

糖尿病 诊断 血清C肽 糖化血红蛋白 准确度

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(20)