Analysis of the Application Value of Aspirin Combined with Rivaroxaban in Patients with Diabetes Mellitus Complicated with Severe Lower Extrem-ity Ischemic Vascular Disease after Operation
Objective To explore the application value of aspirin combined with rivaroxaban in patients with diabetes mellitus complicated with severe lower extremity ischemic vascular disease after operation.Methods A total of 86 pa-tients with diabetes mellitus complicated with severe lower extremity ischemic vascular disease admitted to Zhangpu County Hospital and the Second Affiliated Hospital of Guangzhou Medical University from May 2021 to May 2024 were selected as the research objects and divided into two groups according to different treatment methods,with 43 cases in each group.Both groups were treated with metformin.The control group was given oral aspirin after operation,and the study group was given oral rivaroxaban on the basis of the control group.The blood glucose levels,inflamma-tory factors and incidence of adverse reactions were compared between the two groups.Results After treatment,the levels of fasting plasma glucose,2-hour postprandial plasma glucose,C-reactive protein,interleukin-8 and interleu-kin-6 in the study group were lower than those in the control group,and the differences were statistically significant(all P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The application of aspirin combined with rivaroxaban in patients with diabetes mellitus compli-cated with severe lower extremity ischemic vascular disease after operation can reduce the levels of blood glucose and inflammatory factors,and the risk of adverse reactions is low.
维普
万方数据
