首页|独活寄生汤联合达格列净对糖尿病骨关节炎患者关节功能的影响

独活寄生汤联合达格列净对糖尿病骨关节炎患者关节功能的影响

Effect of Duhuo Jisheng Decoction Combined with Dapagliflozin on Joint Function in Patients with Diabetic Osteoarthritisritis

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目的 探讨独活寄生汤联合达格列净对糖尿病骨关节炎患者关节功能的影响.方法 选取2021年5月—2023年2月泉州泉港仁爱医院收治的145例糖尿病骨关节炎患者为研究对象,根据治疗方式不同分为研究组(n=73)和对照组(n=72).对照组采用达格列净治疗,研究组采用独活寄生汤联合达格列净治疗.比较两组血糖水平、关节功能、炎症反应.结果 治疗后,研究组空腹血糖、餐后2 h血糖、糖化血红蛋白、红细胞沉降率、类风湿因子、C反应蛋白水平均低于对照组,关节功能优于对照组,差异均有统计学意义(P均<0.05).结论 独活寄生汤联合达格列净治疗可降低糖尿病骨关节炎患者的血糖水平,改善关节功能,降低炎性因子水平.
Objective To investigate the effect of Duhuo Jisheng Decoction combined with dapagliflozin on joint func-tion in patients with diabetic osteoarthritis.Methods A total of 145 patients with diabetic osteoarthritis admitted to Quanzhou Quangang Ren'ai Hospital from May 2021 to February 2023 were selected as the research objects.Accord-ing to different treatment methods,they were divided into study group(n=73)and control group(n=72).The control group was treated with dapagliflozin,and the study group was treated with Duhuo Jisheng Decoction combined with dapagliflozin.The blood glucose levels,joint function and inflammatory response were compared between the two groups.Results After treatment,the levels of fasting blood glucose,2-hour postprandial blood glucose,glycated hemo-globin A1c,erythrocyte sedimentation rate,rheumatoid factor and C-reactive protein in the study group were lower than those in the control group,and the joint function was better than that in the control group,the differences were statistically significant(all P<0.05).Conclusion Duhuo Jisheng Decoction combined with dapagliflozin can reduce the blood glucose level of diabetic osteoarthritis patients,improve the joint function,and reduce the level of inflammatory factors.

Duhuo Jisheng DecoctionDapagliflozinDiabetic osteoarthritisJoint functionBlood glucose level

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泉州泉港仁爱医院中医骨伤科,福建 泉州 362000

独活寄生汤 达格列净 糖尿病骨关节炎 关节功能 血糖水平

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(20)