Double-stranded DNA-nucleic acid dye complex-sensitized biocatalytic photosynthesis:Base pairing-switched regeneration of nicotinamide cofactor

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外文摘要：Photo-biocatalysis,the combination of photosensitization and biocatalysis,is an emerging solution for sunlight-based renewable energy.It is thus important to develop light antennas with both good light har-vesting and efficient electron transfer.Herein,the intriguing electrical conductivity of dsDNA and its host effect(for nucleic acid dyes to harvest light)were explored simultaneously to develop a dsDNA-based light antenna for photo-biocatalysis.With SYBR Green Ⅰ(SG)as the example of the nucleic acid dye,the proposed SG-dsDNA system was found to be capable for visible-light-driven reduced nicotinamide adenine dinucleotide(NADH)regeneration,and the turnover frequency of which(1.35 min-1)exceeded most of the existing photocatalytic systems.Since SG can only be hosted by dsDNA,meanwhile dsDNA can be formed through hybridization between single strand DNA and its complementary strand,the pro-posed system adds an extra control of the photocatalytic activity(DNA base pairing-based switch).When integrating the SG-dsDNA system with NADH-dependent horse liver alcohol dehydrogenase(HLADH),successful synthesis of 2-phenylpropanol(a crucial intermediates of profens manufacturing)was achieved.

外文关键词：

PhotosynthesisdsDNASYBR Green ⅠTICT2-phenylpropanol

作者：

Zhen Dong、Yanying Wang、Dan Li、Peng Wu

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作者单位：

College of Chemistry,Sichuan University,Chengdu 610064,Sichuan,China

Analytical & Testing Centre,State Key Laboratory of Hydraulics and Mountain River Engineering,Sichuan University,Chengdu 610064,Sichuan,China

School of Chemistry and Chemical Engineering,Henan Normal University,Xinxiang 453007,Henan,China

基金：

National Natural Science Foundation of ChinaNational Natural Science Foundation of ChinaFundamental Research Funds from Sichuan UniversityOpen Research Fund of School of Chemistry and Chemical Engineering,Henan Normal University

项目编号：

22274102223254032022SCUNL1042022A02

出版年：

2024

DOI：

10.1016/j.jechem.2024.03.017

能源化学

中国科学院大连化学物理研究所中国科学院成都有机化学研究所

能源化学

CSTPCDEI

影响因子：0.654

ISSN：2095-4956

年,卷(期)：2024.94(7)