加速器制备68Ge产额计算方法
Calculation Method for Yield of 68Ge Produced by Cyclotron
高陶 1胡圣 1余伟1
作者信息
- 1. 中广核同位素科技(绵阳)有限公司,绵阳 621000
- 折叠
摘要
68Ga是最具临床应用价值的金属正电子核素之一,通过68Ge/68Ga发生器生产68Ga是一种比较便捷的方式,而母体核素68Ge主要由加速器生产,其中使用较多的一种生产方式是通过质子辐照Ga-Ni合金靶件获得68Ge.准确模拟68Ge产额,对于Ga-Ni合金靶件制备、加速器辐照方案选择和生产准备均有重要意义.本研究提出了一种基于蒙特卡罗方法的加速器生产68Ge的理论产额计算方法,计算了不同条件下质子束流轰击Ga-Ni合金靶件的能量损耗和68Ge理论产额,并通过加速器辐照实验验证了计算结果的可靠性.相关结果可为不同能量质子束流辐照条件下的Ga-Ni合金厚度设计提供参考,对实验结果具有指导意义.
Abstract
68Ga is one of the most clinically valuable metal positron isotopes.Producing 68Ga through a 68Ge/68Ga generator is a relatively convenient way,while the parent nuclide 68Ge is mainly produced by cyclotrons.One of the most commonly used production methods is to obtain 68Ge through proton irradiation of Ga-Ni alloy targets.Accurately simulating the 68Ge yield is of great significance for Ga-Ni alloy target preparation,cyclotron irradiation plan making and production preparation.This paper proposes a method for calculating the theoretical yield of 68Ge produced by cyclotrons based on the Monte Carlo method.The energy loss and 68Ge theoretical yield of proton beam bombardment of Ga-Ni alloy targets under different conditions are calculated.The relevant results can provide reference for Ga-Ni alloy thickness design under different energy proton beam irradiation conditions.The experimental results match well with the calculated results.Finally,the reliability of the calculation results was verified through the cyclotron irradiation experiment,indicating that the theoretical calculation is instructive to the experimental results.
关键词
产额计算/Ga-Ni合金/68Ge/68Ge/68Ga发生器Key words
yield simulation/Ga-Ni alloy/68Ge/68Ge/68Ga generator引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据