The Effect of Isoflavones of Minshan Red Clover on Immune Function and Exercise Capacity in Exercise Rats
OBJECTIVE:This study aims to investigate the influence of isorhamnetin derived from Minshan red clover on immune function and exercise capacity in rats.METHODS:Forty rats were randomly divided into four groups:sedentary group,sedentary with isorhamnetin group,exercise group,and exercise with isorhamnetin group.An incremental exercise load rat model was established to measure exhaustion time,immune organ index,immune globulins,and T lymphocyte subpopulations.RESULTS:After 6 weeks of high-intensity exercise,rats treated with isorhamnetin from Minshan red clover exhibited a significant extension in exhaustion time compared to the corresponding control group.Moreover,there were noticeable increases and variations in immune organ index,T lymphocyte subpopulations(CD4+,CD8+,CD4+/CD8+),and immune globulin levels(IgA,IgG,IgM).CONCLUSIONS:(1)Isorhamnetin from Minshan red clover can markedly enhance exhaustion time in rats undergoing high-intensity endurance training,thereby improving exercise capacity.(2)Isorhamnetin from Minshan red clover impacts the immune system in exercised rats by modulating immune cell function,enhancing immune capabilities,and demonstrating some amelioration in immune suppression.
minshan red cloverisorhamnetinimmune functionexercise capacity
万方数据
维普
