Research Progress on the Molecular Mechanism of Exercise Inhibiting Tumor Incidence and Development
It is widely acknowledged that exercise can reduce cancer incidence and suppress tumorigenesis.Based on the classical organizational principles,this paper summarizes the molecular mechanisms of exercise and tumor,and summarizes the mechanisms of exercise in maintaining tumor proliferation signals,including escaping growth inhibition,resisting cell death,achieving replication immortality,inducing angiogenesis,and activating invasion and metastasis.It is found that exercise directly affects the intrinsic molecular mechanisms of tumors and the systemic effects of exercise to inhibit tumorigenesis.This review indicates that exercise can be an effective strategy for preventing and treating tumors.
exercisetumor incidence and developmentmolecular mechanism