A Meta-analysis of the Effect of Exercise on Serum Irisin Expression Level in Obese Men
OBJECTIVE:This study aims to quantitatively evaluate the effects of exercise on irisin expression in obese men by a meta-analysis.METHODS:This study utilizes literature research method and mathematical statistics.Randomized controlled trials(RCTS)related to exercise,obese men and irisin were collected through CNKI,Wanfang,VIP and PubMed,Embase,Cochrane Library,Web of Science and other English databases.The retrieval period of these experiments was established until April 1,2024,and then the Review Manager 5.4 software was used for data processing.RESULTS:A total of 124 subjects were included in 5 articles in this study.Meta-analysis results showed that compared with the control group,the exercise intervention group could significantly increase serum irisin level[SMD=1.61,95%CI(1.18,2.04),P<0.01].Specifically,the expression level of serum irisin was increased in the aerobic exercise group[SMD=1.73,95%CI(0.77,2.68),P<0.01],while the same was true in the resistance exercise group[SMD=1.50,95%CI(0.82,2.19),P<0.01].The improvement effect was more obvious in aerobic exercise group.CONCLUSION:Exercise training intervention can significantly improve the expression level of serum irisin in obese men.However,compared with the resistance exercise group,the influence of aerobic exercise group on the expression level of serum irisin is more significant.