In view of the phenomenon that the deformation of high-pressure multi-channel valve body is greatly af-fected by the high-pressure fluid in the internal channel of the valve body,the deformation of high-pressure multi-channel valve body is calculated by using the unidirectional fluid structure coupling method in workbench.The three-dimensional model of load sensitive multi-channel valve assembly is established by SolidWorks,the three-di-mensional model is meshed,the coupling calculation of fluid domain and solid domain of multi-channel valve is car-ried out by workbench calculation platform,and the structure of multi-channel valve body is calculated and stud-ied.The calculation results show that the maximum deformation of the multi-channel valve body is located at the position where the pressure compensation chamber flows through the directional valve chamber.The maximum de-formation increases with the increase of the opening amount.When the pressure is 35 MPa and the opening amount is 5.7 mm,the maximum deformation amount is 4.49 um.The maximum stress and strain values of the valve body material are 189.5 MPa and 9.27×10-4,respectively.