To address the unclear understanding of the distribution and hydrocarbon accumulation characteristics of Maokou Formation karst reservoirs in southwestern Sichuan Basin,this study integrated geological,drilling,log-ging,and 3 D seismic data,classified the karst reservoirs,selected seismic attributes for distribution prediction,and analyzed the hydrocarbon accumulation relationships of different karst reservoir types.The study shows that the study area,located in a favorable paleogeomorphic unit,features four types of karst reservoirs developed:top karst,interbed karst,fault-associated karst,and karst collapse.Seismic texture entropy attributes effectively characterize interbed karst bodies and karst collapse.The hydrocarbon accumulation mode of the study area is"self-sourced and self-stored,sourced in lower part and stored in upper part,with efficient transport via faults and fractures."The distribution of Maokou Formation gas reservoirs is jointly controlled by paleogeomorphology,karst reservoir distribu-tion,and fault and fracture systems.The research findings provide crucial support for further Maokou Formation ex-ploration in the area.