Abscisic acid is a kind of plant hormone,which can inhibit plant growth and enhance plant stress resis-tance.It also has therapeutic effect on some animal diseases,and is widely used in agriculture and medicine.Tradi-tional methods of plant extraction and chemical synthesis suffer from high costs,low yields,and high dependence on raw materials.Utilizing microorganisms for abscisic acid synthesis presents a more economical and convenient approach.This article primarily focuses on the metabolic pathway construction for heterologous synthesis of ab-scisic acid,highlighting the current research and production applications utilizing Saccharomyces cerevisiae,Esch-erichia coli,and Yarrowia lipolytica as chassis cells.
Abscisic acidheterologous enzyme expressionenzyme transformationselection of chassis cellsmulti-module tuning
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