Effect of Individualized Lung Protective Ventilation Based on Lung Ultrasound Guidance on Postoperative Lung Function,and Postoperative Cognitive Function in Elderly Patients
Objective To investigate the influence of individualized lung protective ventilation based on lung ultra-sound on postoperative lung function,and postoperative cognitive function in elderly patients.Methods A total of 80 elderly patients under general anesthesia were randomly divided into two groups:traditional lung protective ventilation group(P,group,40 patients)and individualized lung protective ventilation group based on lung ultrasound(P2 group,40 patients).In P1,low tidal volume(VT)was 6 ml/Kg,continuous PEEP was 5cm H2O,and manual lung expansion.In P2,individual lung protective ventilation strategy based on lung ul-trasound was implemented to obtain the best PEEP value and the lung pressure value based on P1 group.Before general anesthesia induction(T0),after removing the tracheal catheter 30min(T1),postoperative 1d(T2),postop-erative 3d(T3)and postoperative 7d(T4),two groups were monitored for oxygen index(OI),respiratory index(RI),respiratory rate(RR),breath rate(RR),C-reactive protein(CRP)concentration,concise mental state as-sessment(MMSE)score,postoperative hospitalization days,and pulmonary complications within 7 days the sur-gery.Results Compared with the T0 point,the OI,the MMSE score and breath holding time significantly de-creased or shortened,while RI,CRP and RR significantly increased or increased(P＜0.05).Compared with P,group,OI and RI decreased significantly from point T1 to T4(P＜0.05);CRP and P2 decreased significantly from T2 to T4(P＜0.05);MMSE in P2 at point T3 and T4(P＜0.05);postoperative hospitalization days P2 were significantly decreased(P＜0.05).The incidence of pulmonary complications within 7 days was significantly low-er in P2 group(P＜0.05).Conclusion Personalized lung protective ventilation based on lung ultrasound is more conducive to the protection of postoperative lung function in elderly patients with laparoscopic radical colon can-cer,has little impact on postoperative cognitive function,and shortens the length of hospital stay,which is wor-thy of clinical recommendation.
lung ultrasoundindividualized lung protective ventilation strategyelderly patientslung functioncognitive function
维普
万方数据
