首页|高帧频超声造影与CT在评估乳腺癌前哨淋巴结状态中的应用价值

高帧频超声造影与CT在评估乳腺癌前哨淋巴结状态中的应用价值

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目的 探讨高帧频超声造影(H-CEUS)及电子计算机断层扫描(CT)在评估乳腺癌腋窝前哨淋巴结(SLN)状态中的应用.方法 随机选取2020年3月~2023年5月于本院行单侧乳腺癌接受手术治疗的54例患者.所有研究对象术前均采用H-CEUS与CT行单侧SLN扫查,共检出72肿大淋巴结,同时记录各自描述SLN的声学图像特点.根据手术治疗后术后SLN组织病理结果,将所有研究对象分为淋巴结非转移组(n=22例)与转移组(n=50例).进一步分析H-CEUS、CT以及以上两种手段联合检测的灵敏度、特异度、阳性预测值、阴性预测值.结果 H-CEUS共检出转移性淋巴结49例和非转移性淋巴结23例,而CT共检出转移性淋巴结47例和非转移性淋巴结25例.与术后病理结果对比分析发现,H-CEUS的灵敏度、特异度、准确度分别为86.00%、72.73%以及81.94%;CT的灵敏度、特异度、准确度分别为78.00%、63.64%与73.61%.H-CEUS联合CT检查的灵敏度、特异度、准确度分别为92.00%、86.36%以及90.28%,均高于单一 H-CEUS、CT检查的诊断效能(P<0.05).结论 H-CEUS、CT能够评估乳腺癌SLN是否存在早期转移性病变,其中高超声造影对乳腺癌的SLN早期转移预测价值较大(P<0.05),两者联合预测价值最大(P<0.05).
The Application Value of High-Frame-Frequency Contrast-Enhanced Ultrasound versus CT in Assessing the Status of Sentinel Lymph Nodes in Breast Cancer
Objective To explore the application of H-CEUS and CT in assessing the status of SLN in breast can-cer.Methods Fifty-four patients who underwent surgical treatment for unilateral breast cancer from March 2020 to May 2023 at our hospital were randomly selected.All study subjects underwent preoperative unilateral SLN scanning using H-CEUS with CT,and a total of 72 enlarged lymph nodes were detected,while the respective acoustic image characteristics describing the SLN were recorded.Based on the histopathological findings of post-operative SLN after surgical treatment,all study subjects were divided into lymph node non-metastatic group(n=22 cases)and metastatic group(n=50 cases).The sensitivity,specificity,positive predictive value,and negative predictive value of H-CEUS,CT,and the combined detection of the above two means were further analyzed.Results H-CEUS detected a total of metastatic lymph node cases and non-metastatic lymph node cases,while CT detected a total of metastatic lymph node cases and non-metastatic lymph node cases.Comparison with post-operative pathological results showed that the sensitivity,specificity and accuracy of H-CEUS were 86.00%,72.73%and 81.94%,respectively,while those of CT were 78.00%,63.64%and 73.61%,respectively.The sensi-tivity,specificity,and accuracy of H-CEUS combined with CT were 92.00%,86.36%,and 90.28%,respectively,which were higher than those of single H-CEUS and CT(P<0.05).Conclusion H-CEUS and CT were able to assess the presence of early metastatic lesions in SLN of breast cancer,in which high-frequency ultrasonography had a greater predictive value of early metastasis in SLN of breast cancer(P<0.05),and the combination of the two had the greatest predictive value(P<0.05).

breast cancersentinel lymph nodehigh-frame-frequency contrast-enhanced ultrasoundCT

高文祥、尹明

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南京医科大学附属泰州人民医院,江苏 泰州 225300

乳腺癌 前哨淋巴结 高帧频超声造影 CT

2024

泰州职业技术学院学报
泰州职业技术学院

泰州职业技术学院学报

影响因子:0.285
ISSN:1671-0142
年,卷(期):2024.24(5)