首页|不同肝功能分级患者食管非密集套扎预后评价

不同肝功能分级患者食管非密集套扎预后评价

扫码查看
目的 观察内镜下非密集套扎疗法对肝功能 B级(Child-Pugh B级)、肝功能 C级(Child-Pugh C级)患者食管静脉曲张治疗效果的判断,分析肝功能分级差的患者经套扎治疗后的预后效果是否劣于肝功能分级好的患者.方法 选取 2007 年至 2013 年在昆明医科大学第一附属医院收治的肝硬化并食管静脉曲张患者 76 例,男 47 例,女 29 例,平均年龄 55 岁.试验组:肝功能 B 级,40 例;对照组;肝功能 C级,36 例,均采用六连发套扎器行内镜下治疗,套扎圈≤6 个为非密集套扎.结果 试验组、对照组首次平均套扎次数相比,差异无统计学意义(t=1.551,P=0.125);两组套扎首次治愈相比,差异无统计学意义(χ2 = 0.085,P>0.05);两组首次套扎总有效率、半年后复查总有效率、1 年后复查总有效率、2 年后复查总有效率、3 年后复查总有效率相比,差异有统计学意义(P<0.05).结论 肝功能分级的轻重可影响食管静脉曲张套扎患者手术治疗后的预后情况.长远看来肝功能 B 级患者预后较肝功能 C级患者好,临床医师对患者进行静脉曲张套扎治疗前需认真评估肝功能水平.
Evaluation of treatment prognosis of patients with different liver function by esopha-geal non-intensive ligation
Objective To observe the effect of endoscopic non-intensive ligation therapy on esophageal varices in pa-tients with liver function grade B(Child-Pugh grade B)and liver function grade C(Child-Pugh grade C),and analyze whether the prognosis of patients with poor liver function grade after ligation is worse than that of patients with good liver function grade.Methods A total of 76 patients with cirrhosis and esophageal varices admitted to the First Affiliated Hospital of Kunming Medical University from 2007 to 2013 were selected,including 47 males and 29 females with an av-erage age of 55 years.Experimental group:liver function grade B,40 cases;Control group.All 36 cases with grade C liver function underwent endoscopic treatment with six consecutive ligation devices,with ligation rings≤6 as non-dense ligation.Results There was no significant difference in the average number of first ligation between the experimental group and the control group(t=1.551,P=0.125).There was no significant difference between the two groups(χ2= 0.085,P>0.05).The total effective rate of the first ligation,after half a year,after 1 year,after 2 years,3 years were statistically significant difference between the two groups(P<0.05).Conclusion The degree of liver function can af-fect the prognosis of esophageal variceal ligation patients after operation.In the long run,the prognosis of patients with grade B liver function is better than that of patients with grade C liver function.Clinicians should carefully evaluate the liver function grade before performing varicose ligation treatment.

CirrhosisEsophageal varicesNon-dense ligationChild-Pugh class

彭亚诗、胡孟婷、彭俊、何君一、南琼

展开 >

贵州省人民医院消化内科,贵州 贵阳 550000

中国人民解放军总医院第四医学中心重症医学科

贵州省人民医院内分泌科

昆明医科大学第一附属医院消化内科

展开 >

肝硬化 食管静脉曲张 非密集套扎 肝功能分级

云南省教育厅科学研究基金项目

2015Z071

2024

胃肠病学和肝病学杂志
郑州大学

胃肠病学和肝病学杂志

CSTPCD
影响因子:1.029
ISSN:1006-5709
年,卷(期):2024.33(1)
  • 2