Study of mesenchymal stem cells in primary biliary cholangitis
Primary biliary cholangitis(PBC)is a chronic autoimmune cholestatic liver disease.In recent years,studies have found that mesenchymal stem cells(MSCs)are becoming a new way to treat liver diseases due to their characteristics of immune regulation,anti fibrosis and hepatocyte differentiation.More and more evidence shows that MSCs have a positive role in the treatment of PBC.This article reviewed the pathogenesis of PBC,the mechanism of MSCs in the treatment of PBC,and research progress.MSCs have a broad prospect in the treatment of PBC,which is worthy of further study.
Mesenchymal stem cellsPrimary biliary cholangitisAnimal experimentClinical research