Research progress of biomarkers in inflammatory bowel disease
Inflammatory bowel disease(IBD)mostly includes ulcerative colitis(UC)and Crohn's disease(CD).Its diagnosis and prognosis are challenging because that most clinical symptoms are not specific to IBD.To date,there is no gold standard test for monitoring IBD.Endoscopy and imaging are essential diagnostic tools that provide information about disease status,location,and severity.However,the invasive nature and high cost of endoscopy make it unsuitable for frequent monitoring of disease activity in patients with IBD,and currently available blood and fecal based biomarkers provide reusable quantitative tools that can complement clinical assessment and help clinicians diagnose and treat IBD.Advances in genome,proteome and microbiome technologies have facilitated the development of new biomarkers for IBD.Reviews of the literature showed that there is a lack of summary of biomarkers for IBD detection.This review re-viewed the available biomarkers and presented the latest advances in the discovery of IBD biomarkers.
NETL
NSTL
万方数据
维普
