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联合疗法在炎症性肠病中的应用进展

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炎症性肠病(inflammatory bowel disease,IBD)是一种难治性肠道炎症性疾病,药代动力学的失效及药效学逃逸导致目前以单一靶向治疗为主的方案受到限制,而对于重症及肠外表现的治疗不尽如人意,加速了人们研究联合疗法的进度,既往比较成熟的联合治疗案例进一步推动双靶向治疗方案的研究,该文就 IBD联合疗法作一概述.
Research progress on combination therapy in inflammatory bowel disease
Inflammatory bowel disease(IBD)is a refractory intestinal inflammatory disease,the failure of pharmaco-kinetics and pharmacodynamic evasion has led to the current single-targeted therapy based treatment is restricted,and the unsatisfactory treatment of severe and extraparenteral manifestations has accelerated the progress of research on com-bination therapy.The previous mature combination therapy cases have further promoted the research of dual-targeted therapy regimens.This article reviewed the combination therapy for IBD.

Inflammatory bowel diseaseCombination therapyDual-targeted therapy

彭雯、罗超、孙志广

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南京中医药大学第二附属医院脾胃科,江苏 南京 210017

南京中医药大学

炎症性肠病 联合疗法 双靶向治疗

国家自然科学基金青年科学基金江苏省第二中医院中青年科技菁英项目南京中医药大学自然科学基金

82104792SEZJY2023014XZR2023067

2024

胃肠病学和肝病学杂志
郑州大学

胃肠病学和肝病学杂志

CSTPCD
影响因子:1.029
ISSN:1006-5709
年,卷(期):2024.33(2)
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