磁共振质子密度脂肪分数在非酒精性脂肪性肝病诊断中的应用现状
Advances in the application of magnetic resonance imaging-proton density fat frac-tion in diagnosing non-alcoholic fatty liver disease
卫小蝶 1齐石 1赵锦涵 1张晶1
作者信息
- 1. 首都医科大学附属北京佑安医院肝病中心三科,北京 100069
- 折叠
摘要
非酒精性脂肪性肝病(non-alcoholic fatty liver disease,NAFLD)已成为我国乃至全球慢性肝病的主要病因,包括非酒精性脂肪肝(non-alcoholic fatty liver,NAFL)、非酒精性脂肪性肝炎(non-alcoholic steatohepatitis,NASH)和肝硬化,最终发展为肝细胞癌(hepatocellular carcinoma,HCC).早期诊断NAFLD对预防肝脏相关疾病的进展及相关并发症有重要的临床意义.肝脏脂肪变性作为 NAFLD的一个基本组织学特征,准确评估和量化肝脏脂肪尤为重要,磁共振测量的质子密度脂肪分数作为无创性定量诊断肝脏脂肪的影像学方法,可以帮助临床医师及时诊断及治疗.本文对质子密度脂肪分数在 NAFLD诊断中的研究进展作一综述.
Abstract
Non-alcoholic fatty liver disease(NAFLD)has become the main cause of chronic liver disease in China and even the world,including non-alcoholic fatty liver(NAFL),non-alcoholic steatohepatitis(NASH)and cirrhosis,and eventu-ally developing into hepatocellular carcinoma(HCC).Early diagnosis of NAFLD has important clinical significance in pre-venting the progression of liver-related diseases and complications.Hepatic steatosis,which is a basic histological feature of NAFLD,is particularly important to accurately assess and quantify liver fat.MRI-derived proton density fat fraction,as a noninvasive imaging method for quantitative diagnosis of liver fat,can help clinicians diagnose and treat the disease in time.This article reviewed the research progress of proton density fat fraction in the diagnosis of NAFLD.
关键词
非酒精性脂肪性肝病/质子密度脂肪分数/脂肪定量Key words
Non-alcoholic fatty liver disease/Proton density fat fraction/Fat quantification引用本文复制引用
基金项目
首都卫生发展科研专项(2022-2Z-2187)
出版年
2024
NETL
NSTL
万方数据