Effects of Helicobacter pylori eradication on microbiota of digestive tract
Helicobacter pylori(H.pylori)infection is a significant risk factor for gastritis and gastric cancer and is estimated to affect approximately 50%of the world's population.Both the Chinese Consensus and Maastricht Ⅵ Consen-sus have highlighted the importance of individual eradication for infected patients.The recommended triple or quadruple eradication regimen includes antibiotics and acid inhibitors,which can impact the microbiota in digestive tract.In recent years,a novel regimen with high-dose Amoxicillin dual therapy has emerged,but its impact on the microbiota of diges-tive tract is not well understood.At present,the effects of eradication regimens on oral and gastrointestinal microflora have attracted much clinical concern.This review aimed to summarize the impact of different eradication regimens on the oral and gastrointestinal microbiota,as well as the role of probiotics in the restoration of digestive tract microbiota.
Helicobacter pyloriEradication treatmentMicrobiota of digestive tractProbiotics
NETL
NSTL
万方数据
