首页|结直肠无蒂锯齿状病变研究进展

结直肠无蒂锯齿状病变研究进展

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根据2019年WHO对消化系统肿瘤的分类,锯齿状息肉(serrated polyposis,SP)分为增生性息肉(hyperplastic polyp,HP)、无蒂锯齿状病变(sessile serrated lesions,SSL)、SSL 伴发育不良(SSL with dysplasia,SSLD)、传统锯齿状腺瘤(traditional serrated ade-noma,TSA)和未分类的锯齿状腺瘤.SSL被认为具有恶性潜能,尤其是出现细胞异型增生后,可快速进展至结直肠癌(colorectal cancer,CRC),SSL患病率并不低,但我国的检出率却远低于国际平均水平,加强对SSL的认识至关重要.本文基于文献综述了 SSL的相关危险因素、组织学表现、分子生物标志物、内镜表现及内镜下治疗、监测的最新研究进展.
Advances in the study of sessile serrated lesions of colorectal
According to the classification of digestive system tumors by the WHO in 2019,serrated polyposis(SP)can be classified as hyperplastic polyp(HP),sessile serrated lesions(SSL),SSL with dysplasia(SSLD),traditional serrated adenoma(TSA)and unclassified serrated adenoma.SSL is considered to have malignant potential,especially after the appearance of cell dysplasia,can progress rapidly to colorectal cancer(CRC).The prevalence of SSL is not low,but our detection rate is far lower than the international average level,therefore,it is very crucial to strengthen the understanding of SSL.Based on the literature,this paper reviewed the latest research progress of SSL related risk factors,histological findings,molecular biomarkers,endoscopic findings,endoscopic therapy and postoperative moni-toring.

Sessile serrated lesionsBiomarkersEndoscopySupervision

吴竹君、郜敏杰、申慧琴

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山西医科大学,山西太原 030000

山西医科大学第二医院消化内科

无蒂锯齿状病变 生物标志物 内镜 监测

2024

胃肠病学和肝病学杂志
郑州大学

胃肠病学和肝病学杂志

CSTPCD
影响因子:1.029
ISSN:1006-5709
年,卷(期):2024.33(7)