Advances in the application of Azathioprine in autoimmune liver disease
Autoimmune liver disease(AILD)is a special type of chronic liver disease caused by immune dysfunc-tion.Immunosuppressive therapy is the main drug treatment for AILD,and Azathioprine is widely used in AILD among immunosuppressive agents.This paper introduced the mechanism of action of Azathioprine in AILD.At the same time,the specific applications in AILD including autoimmune hepatitis,primary biliary cirrhosis,primary sclerosing cholangi-tis,IgG4-related sclerosing cholangitis,overlapping syndrome and other diseases were summarized.The side effects and limitations of the clinical application of this drug were summarized,providing ideas for clinical treatment of AILD.
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