脂质组学在胃癌中的研究进展
Research progress of lipidomics in gastric cancer
王海玉 1丁宇敏 1李德红2
作者信息
- 1. 甘肃中医药大学公共卫生学院,甘肃兰州 730000
- 2. 甘肃省人民医院检验科
- 折叠
摘要
脂代谢异常和脂质代谢重编程与肿瘤发生发展密切相关.脂质组学作为近年来兴起的"组学",通过全面系统分析肿瘤患者的脂质及其相互作用的分子和代谢物,揭示肿瘤发病机制.脂质组学为寻找胃癌的预测、早期诊断、治疗、预后等生物标志物和生物靶点提供了新思路.
Abstract
Abnormal lipid metabolism and lipid metabolic reprogramming are closely related to the development of tumor.Lipidomics,as an emerging omics in recent years,can reveal the pathogenesis of tumor through comprehensive and systematic analysis of lipids,the molecules and metabolites with which they interact in tumor patients.Lipidomics provides new ideas for screening biomarkers and biological targets for the prediction,early diagnosis,treatment and prognosis of gastric cancer.
关键词
胃癌/脂质组学/脂质/生物标志物/生物靶点Key words
Gastric cancer/Lipidomics/Lipids/Biomarkers/Biological targets引用本文复制引用
基金项目
甘肃省自然科学基金(20JR5RA146)
出版年
2024
NETL
NSTL
万方数据