首页|相关离子与肝性脑病的关系及其致病机制的研究进展

相关离子与肝性脑病的关系及其致病机制的研究进展

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肝性脑病是肝硬化患者严重的并发症,预后较差.目前已知氨在肝性脑病的发病过程中占据中心地位,但随着研究的深入,血钠离子、氯离子、锌离子、镁离子也被发现与肝性脑病发病相关;本文通过回顾相关研究,对相关离子与肝性脑病的关系及其致病机制展开综述,以期为临床肝性脑病的诊疗提供新思路.
Research progress on the relationship between related ions and hepatic encephalopathy and its pathogenic mechanism
Hepatic encephalopathy is a serious complication in patients with liver cirrhosis with poor prognosis.At present,it is known that ammonia plays a central role in the pathogenesis of hepatic encephalopathy,but with the deepe-ning of research,blood sodium ion,chloride ion,zinc ion and magnesium ion have also been found to be related to the pathogenesis of hepatic encephalopathy.The relationship between related ions and hepatic encephalopathy and its patho-genic mechanism were reviewed in order to provide new ideas for the diagnosis and treatment of clinical hepatic encepha-lopathy.

Blood ammoniaRelated ionsHepatic encephalopathyPathogenic mechanism

田梦、武国兵、刘敏、郑亚、陈兆峰

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兰州大学第一临床医学院,甘肃 兰州 730000

兰州大学第一医院消化科

兰州大学第一医院消化内镜中心

兰州大学第一医院,甘肃省胃肠病重点实验室

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血氨 相关离子 肝性脑病 致病机制

甘肃省自然科学基金兰州市科技计划项目兰州大学第一医院院内基金

21JR1RA0732021-1-111ldyyyn2021-6

2024

胃肠病学和肝病学杂志
郑州大学

胃肠病学和肝病学杂志

CSTPCD
影响因子:1.029
ISSN:1006-5709
年,卷(期):2024.33(8)