Application of Vonoprazan in Helicobacter pylori eradication therapy
Helicobacter pylori(H.pylori)infection is a common chronic bacterial infection associated with a variety of gastrointestinal diseases.Domestic and foreign consensus recommends that H.pylori eradication programs are based on acid inhibitors.Vonoprazan is a new type of acid inhibitor with a stronger acid inhibition than commonly used proton pump inhibitors(PPI).The eradication effect of H.pylori based on Vonoprazan program is not inferior to PPI,and it is well tolerated.Wide application of Vonoprazan program is expected to further improve the H.pylori eradication rate.This article reviewed the use of Vonoprazan for primary and secondary treatment of H.pylori infection,the eradication of refractory H.pylori and penicillin-allergic H.pylori infection,and the safety of Vonoprazan,aiming to evaluate the clini-cal application value of Vonoprazan in the eradication treatment of H.pylori infection.
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