Research progress of P-CAB drugs in eradication of Helicobacter pylori
Helicobacter pylori(H.pylori)infection is one of the most H.pylori infectious disease in the world.H.pylori is closely associated with many gastrointestinal diseases.Eradication of H.pylori can effectively reduce the risk of infection.At present,the proton pump inhibitor bismuth-based quadruple therapy is considered to be an effective reg-imen for the eradication of H.pylori.Now because of the lack of acid inhibition,antibiotic resistance to increase and oth-er factors leading to the reduction of H.pylori eradication rate.A new type of potassium-competitive acid blocker(P-CAB)is coming into being,which may improve the eradication rate of H.pylori.This article reviewed the clinical research progress of H.pylori eradication with P-CAB.