Clinical characteristics of endoscopic diagnosis and treatment of portal hypertensive gastropathy
Objective To investigate the clinical and endoscopic characteristics of portal hypertension gastropathy and its relationship with endoscopic treatment of esophageal varices,to provide evidences for prevention and treatment of disease.Methods Patients with liver cirrhosis associated with esophageal varices were enrolled for gastroscopy exami-nation,and the degree of esophageal varices and portal hypertension gastropathy with patients were recorded.The data of gender,body weight,serum biochemical index and liver function scoring were collected.The data of following-up with patients after endoscopic esophageal varices hardener or ligation were performed.These clinical data were statistically analyzed.Results A total of 162 cases of liver cirrhosis with esophageal varices patients were included,and the detec-tion rate of portal hypertension gastropathy with patients was 53.7% ,and there were statistically significant differences in the levels of serum white blood cells,hemoglobin,platelets and ammonia between portal hypertension gastropathy and without portal hypertension gastropathy in patients(P<0.01).There were significant differences in liver function scoring in different severities with portal hypertensive gastropathy in 87 patients(P<0.01).The incidence of non-esophageal and gastric varices hemorrhage caused by portal hypertensive gastropathy was 77.2% .After endoscopic treatment,the proportion of moderate and severe portal hypertensive gastropathy were increased from 28.6% to 71.4% ,and the difference was statistically significant compared with before endoscopic treatment in 35 cases with esophageal var-ices patients(P<0.01).Conclusion The incidence of portal hypertensive gastropathy was high in patients with portal hypertension,which has become one of the main causes of hemorrhage in patients with liver cirrhosis.Paying attention to the influence of endoscopic treatment of esophageal varices in disease will provides the basis for the diagnosis and treatment of gastrointestinal hemorrhage associated with portal hypertension.
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