A comparative study of chronic atrophic gastritis and gastric cancer in Jiuxianqiao area based on questionnaire survey combined with new gastric cancer screening sco-ring system
Objective To explore the application value of questionnaire survey combined with new gastric cancer screening scoring system in the diagnosis of chronic atrophic gastritis and gastric cancer in Jiuxianqiao district of Beijing,Evaluate the screening population for gastroscopy,practice individualized medical services,avoid the waste of medical resources,and preliminarily explore the prevention and treatment strategy of gastric cancer.Methods A total of 291 patients with symptoms of upper abdominal discomfort admitted to the First Affiliated Hospital of Tsinghua University from Mar.2022 to Nov.2022(including the cooperative unit-Jiangtai Community,Dongfeng Community and Gaojiayuan Community)were included as analysis objects.Preliminary screening for gastric cancer was carried out through ques-tionnaire survey combined with the new gastric cancer screening scoring system(hereinafter referred to as the compre-hensive scoring system)and the single application of the new gastric cancer screening scoring system.Combined with the preliminary screening results,the population was divided into low-risk group,medium-risk group and high-risk group,and the detection rates of chronic non-atrophic gastritis,chronic atrophic gastritis and gastric cancer after gastros-copy were compared among the three groups.Results A total of 291 patients participated in gastroscopy,and the com-prehensive scoring system was used.There were 156(53.61% )patients in the low-risk group,108(37.11% )patients in the medium-risk group,and 27(9.28% )patients in the high-risk group.In terms of the detection rate of chronic atrophic gastritis and gastric cancer,the high-risk group was higher than the medium-risk group and low-risk group,with significant difference among the three groups(P<0.05).Meanwhile,ROC analysis showed that the AUC of the compre-hensive scoring system and the new gastric cancer screening scoring system for the diagnosis and evaluation of chronic atrophic gastritis and gastric cancer were 0.658(0.595-0.721)and 0.684(0.622-0.746),respectively,with the sensitivity were 62.22% ,63.70% ,and specificity were 67.31% ,63.70% ,respectively;the positive predictive values were 0.622 and 0.652,and the negative predictive values were 0.673 and 0.692,respectively.The AUC of the com-prehensive score system and the new gastric cancer screening scoring system were 0.756(0.583-0.929)and 0.717(0.552-0.882),respectively.The sensitivity were 50.00% ,80.00% ,and specificity were 92.17% ,55.87% ,re-spectively.The positive predictive values were 0.179 and 0.130,and the negative predictive values were 0.981 and 0.974,respectively.Conclusion The questionnaire survey combined with the new gastric cancer screening scoring system has a good screening value for gastric cancer in Jiuxianqiao area of Beijing,and is worthy of clinical promotion,which can lay a foundation for the establishment of large-scale gastric cancer risk assessment system.
Questionnaire surveyNew gastric cancer screening scoring systemGastroscopyGastric cancerChro-nic atrophic gastritis
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