肠道菌群在炎症性肠病相关肠纤维化中的作用研究进展
Advances in the role of intestinal flora in intestinal fibrosis associated with inflam-matory bowel disease
王硕 1苏文豪 1刘传 1董卫国1
作者信息
- 1. 武汉大学人民医院消化内科,湖北 武汉 430060
- 折叠
摘要
炎症性肠病包括溃疡性结肠炎和克罗恩病,肠纤维化是其常见的晚期并发症之一,目前仍无较好的非手术治疗手段.肠道菌群与 IBD的发生发展密切相关,且已在多种器官纤维化中证实其作用.本文将就已有的肠道菌群在 IBD相关肠纤维化中的研究进展作一综述,以期为明确 IBD患者中肠道菌群和肠纤维化的相互作用提供参考依据.
Abstract
Inflammatory bowel disease includes ulcerative colitis and Crohn′s disease,for which intestinal fibrosis is one of the common late complications and for which there is still no better non-surgical treatment.Intestinal flora is closely associated with the development of IBD and its role has been demonstrated in a variety of organ fibrosis.In this paper,we reviewed the available research progress on intestinal flora in IBD-related intestinal fibrosis to provide a refer-ence for clarifying the interaction between intestinal flora and intestinal fibrosis in IBD patients.
关键词
肠道纤维化/肠道菌群/益生菌/炎症性肠病Key words
Intestinal fibrosis/Intestinal flora/Probiotics/Inflammatory bowel disease引用本文复制引用
出版年
2024
NETL
NSTL
万方数据