Research progress of Helicobacter pylori infection and eradication of related mecha-nisms affecting intestinal microecological disorders
Helicobacter pylori(H.pylori)is a common pathogenic bacterium that causes acute and chronic gastroin-testinal diseases and parenteral diseases.Eradication of H.pylori plays a key role in the treatment.The global infection rate of H.pylori is always high,and in recent years,the eradication effect of H.pylori is poor due to H.pylori drug resist-ance and other mechanisms.H.pylori infection and its eradication process can also affect the changes of intestinal micro-ecology,and its mechanism is extremely complex,which is a hot topic in the medical field.This paper summarized the latest literature on the mechanism of intestinal microecological disturbance caused by H.pylori infection and eradication,in order to provide certain theoretical basis for how to reduce the change and imbalance of intestinal flora during clinical anti-H.pylori treatment,so as to improve the curative effect of H.pylori eradication and reduce the adverse reactions caused by eradication treatment.