Clinical analysis of 161 cases of ischemic colitis
Objective To analyze and compare the clinicopathologic features and clinical outcomes of ischemic coli-tis in patients of different ages,so as to enhance the understanding of the disease.Methods The clinical features,risk factors,laboratory examination,imaging,colonoscopy and histopathology,ischemic degree and clinical outcomes of 161 patients diagnosed with ischemic colitis by colonoscopy in our hospital from Jan.2017 to Dec.2022 were retrospectively analyzed.At the same time,according to age,they were divided into the young and middle-aged group(68 cases＜60 years old)and the elderly group(93 cases ≥60 years old),and the differences of relevant factors between different ages were analyzed.Results The age of 161 patients with ischemic colitis was(62.19±11.22)years old,mainly fe-male(58.4％),and the elderly group accounted for 57.8％.It is often combined with risk factors such as hyperten-sion,history of abdominal surgery,and history of malignant tumor,and there were statistically significant differences in hypertension between the two groups(P＜0.05).The main clinical manifestations were abdominal pain,followed by he-matochezia and diarrhea.There was no statistically significant difference in clinical manifestations among different age groups.The laboratory tests were mainly positive for fecal occult blood,elevated D-dimer and CRP.The positive rate of ultrasonography was low,and the findings of CT were mainly inflammatory changes of intestinal wall.Endoscopic lesions mainly involved the left half colon(73.3％),and the sigmoid colon(72.7％)was the main lesion,and the differences between the two groups in the right colon and extensive colon were statistically significant(P＜0.05).The stage of colonoscopy was stage Ⅰ or Ⅱ,and there was no significant difference in stage between the two groups(P＞0.05).Under endoscopy,the main manifestations were mucosal hyperemia and edema,erosion and multiple ulcers,and the histopathology was mostly acute and chronic mucosal inflammation.There were statistically significant differences in the degree of ischemia among different age groups(P＜0.05).A total of 159 patients(98.8％)improved after treat-ment.Conclusion Ischemic colitis usually occurs in the elderly and is associated with high blood pressure,history of abdominal surgery,history of malignant tumor and other risk factors.The degree of ischemia in elderly patients is more severe and more involved in the right half colon.The degree of ischemia in young and middle-aged patients is mild,more involving extensive colon.Ischemic enteritis is a self-limited disease,and the prognosis is good after timely treatment.
万方数据
维普
