Colorectal cancer(CRC)is a disease with high morbidity and high mortality worldwide,and its etiology is multiple and intertwined.Multiple studies have confirmed that the effects and complications of colorectal tumor immuno-therapy are related to the composition of specific gut microbiota,and adjuvant therapy that modulates this part of the mi-crobiota is expected to maximize the effect of CRC immunotherapy.We summarized the scientific evidence for the role of gut microbiota in CRC immunotherapy,focusing on the current status of specific microbiota and microbiota modulation-related treatment regimens in CRC immunotherapy.
关键词
肠道菌群/结直肠癌/免疫抑制剂/精准医疗/中医药
Key words
Gut flora/Colorectal cancer/Immunosuppressants/Precision medicine/Traditional Chinese medicine