Progress and future prospects of immunotherapy for colorectal cancer assisted by gut flora
Colorectal cancer(CRC)is a disease with high morbidity and high mortality worldwide,and its etiology is multiple and intertwined.Multiple studies have confirmed that the effects and complications of colorectal tumor immuno-therapy are related to the composition of specific gut microbiota,and adjuvant therapy that modulates this part of the mi-crobiota is expected to maximize the effect of CRC immunotherapy.We summarized the scientific evidence for the role of gut microbiota in CRC immunotherapy,focusing on the current status of specific microbiota and microbiota modulation-related treatment regimens in CRC immunotherapy.
Gut floraColorectal cancerImmunosuppressantsPrecision medicineTraditional Chinese medicine