原发性肾上腺血管肉瘤临床病理分析并文献复习
Primary adrenal angiosarcoma:a clinicopathological analysis and review of the literature
刘浩茹 1曹杰 2周兵3
作者信息
- 1. 九江市第一人民医院病理科
- 2. 九江市第一人民医院影像中心
- 3. 九江学院第二附属医院病理科,九江 332000
- 折叠
摘要
本文报道了1例原发性肾上腺血管肉瘤(PAA)患者.女性,年龄52岁.体检B超发现左肾上极占位就诊.镜下见肾上腺结构破坏,代之大小不一的相互沟通的血管网浸润性生长,内皮细胞异型明显,核大、深染,核分裂可见.免疫表型:PAA瘤细胞表达Vim、CD34、CD31、ERG及F8,不表达CD117、HHV8、S-100、SMA和D2-40,Ki67 增殖指数约 20%.该疾病罕见,确诊需结合组织学形态及免疫组化标记,早期诊断,早期完整肿瘤切除,可改善预后.
Abstract
A case of primary adrenal angiosarcoma(PAA)is reported.Female,age 52.Physical examination B ultrasound found that the upper pole of the left kidney was occupied.Under the microscope,the adrenal gland struc-ture was destroyed and replaced by the invasive growth of the interconnected vascular network of different sizes,the endothelial cells were obviously deformed,the nuclei were large and deeply stained,and the nuclear division was visi-ble.Immunophenotype:PAA tumor cells expressed Vim,CD34,CD31,ERG and F8,but did not express CD117,HHV8,S-100,SMA and D2-40,and the proliferation index of Ki67 was about 20%.This disease is rare,diagnosis needs to be combined with histological and immunohistochemical markers,early diagnosis,early complete tumor re-section,can improve the prognosis.
关键词
血管肉瘤/肾上腺肿瘤/病理学,临床Key words
angiosarcoma/adrenal neoplasm/pathology,clinical引用本文复制引用
出版年
2024
NETL
NSTL
万方数据